Skin Biopsy in Cagliari: Histological Diagnosis

    The definitive examination for suspicious skin lesions.

    A skin biopsy is the definitive diagnostic test for many skin conditions. At Centro Eudermia in Cagliari we perform biopsies under local anaesthesia using a minimally invasive technique. The histological examination is carried out at accredited external pathology laboratories.

    • Punch, excisional or incisional biopsy on site
    • Local anaesthesia, outpatient procedure
    • Histological examination performed at accredited external laboratories
    • Explanation of the report and treatment pathway

    What a Skin Biopsy Is

    The most accurate diagnostic procedure in dermatology

    Histological diagnosis

    The gold-standard test

    A skin biopsy allows a precise diagnosis through microscopic analysis of the sampled tissue. It is the definitive test for clarifying the nature of a suspicious lesion.

    Technique tailored to the lesion

    Punch, excisional, shave

    The sampling technique is chosen according to the type, location and size of the lesion, with the aim of obtaining a representative sample while minimising the aesthetic impact.

    Outpatient procedure

    Under local anaesthesia

    The biopsy is performed in the clinic on an outpatient basis, under local anaesthesia. The procedure takes just a few minutes and does not require complex preparation.

    Analysis at accredited laboratories

    Report interpreted by our dermatologist

    The sample is sent to accredited external pathology laboratories for the definitive histological examination. The dermatologist at Centro Eudermia then interprets the report and recommends the most appropriate next steps.

    The Procedure

    How a skin biopsy is performed

    1

    Preparation

    Disinfection and local anaesthesia of the area.

    2

    Sampling

    Taking the sample with the appropriate technique.

    3

    Closure

    Closing the wound with sutures if necessary.

    Frequently Asked Questions

    Is the biopsy painful?

    No, it is performed under local anaesthesia. You only feel the initial prick of the anaesthetic.

    How long for the results?

    The histological examination is carried out at external pathology laboratories; the time it takes for the report to become available depends on the processing laboratory. Once it is received, the dermatologist at Centro Eudermia will explain the results and outline the treatment pathway.

    Will there be a scar?

    The scar depends on the size of the sample, but it is generally minimal.

    Do I have to stop taking any medication?

    Let us know if you take anticoagulants or antiplatelet medication. It may be necessary to stop them.

    Can I shower afterwards?

    It is best to keep the area dry for 24-48 hours, then follow the instructions provided.

    When will the histology report arrive?

    The histological examination is carried out at accredited external pathology laboratories. The time it takes for the report to become available depends on the processing laboratory and generally ranges from 7 to 21 days. We will contact you as soon as the report is available to arrange a follow-up appointment to explain it.

    What happens once the report is received?

    Once the histology report is received, the dermatologist at Centro Eudermia will explain the results and outline the most suitable treatment pathway. For lesions that require further treatment (e.g. wider excision or referral to the hospital oncology centre), we will guide the patient through the next steps.

    Is a biopsy always necessary for suspicious skin lesions?

    Not always. Many lesions can be diagnosed clinically with a dermoscopic examination alone. A biopsy is proposed when the lesion shows uncertain clinical or dermoscopic features that require histological confirmation to define the diagnosis and the treatment pathway.

    When a Biopsy Is Necessary

    A biopsy is performed when the clinical diagnosis is inconclusive and histological certainty is needed to guide treatment.

    Suspicious pigmented lesions

    Moles showing atypical features on dermoscopy

    Suspicious non-pigmented lesions

    Nodules, non-healing ulcers, persistent papules

    Diagnostic confirmation of skin cancers

    Melanoma, basal cell carcinoma, squamous cell carcinoma

    Atypical inflammatory diseases

    That do not respond to standard therapies

    Autoimmune skin diseases

    Lupus, pemphigus, vasculitis

    Atypical infections

    That require identification of the causative pathogen

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    Reviews translated from the original Italian

    “I went to the doctor for a dermatological removal. As well as being extremely kind, she was excellent and very gentle. Very meticulous throughout the visit. I had a great experience and will definitely go back.”

    Margherita G.2025

    A Definite Diagnosis

    A biopsy is the gold standard for diagnosing skin lesions. Don't put it off.